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. 2020 Mar 3;2020(3):CD001838. doi: 10.1002/14651858.CD001838.pub6

Janko 1998.

Methods Trial design: parallel
 Single centre, Slovakia
Participants Couples with unexplained subfertility
N randomised: 72
 Age: not stated
 Duration of subfertility: > 3 yrs
 Basic fertility work‐up normal, semen normal not further specified
 Previous treatment: not stated
Interventions Comparison: IUI + OH versus TI + OH
 Stimulation method: hMG (10 amp per cycle)
 Ovulation: 10,000 IU hCG
 Timing: not specified
 No cancellation criteria were given
 Duration of treatment: 3 cycles max
Outcomes PR per cycle
Pregnancy not further defined
Notes ITT analysis: possible
 Abstract only
 Data calculated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not stated
Allocation concealment (selection bias) Unclear risk Unclear; not stated
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Blinding was not possible because of the nature of the interventions
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Blinding was not possible because of the nature of the interventions and non‐blinding was not likely to affect the outcomes of interest
Incomplete outcome data (attrition bias) 
 All outcomes High risk Not available
Selective reporting (reporting bias) High risk In this abstract the reported outcome data are minimal
Other bias Unclear risk Insufficient information available to evaluate this risk domain