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. 2020 Mar 2;2020(3):CD005004. doi: 10.1002/14651858.CD005004.pub3

Inoue 1998.

Study characteristics
Methods HCC in Japan
Participants Participants: 127,477 inhabitants of 45 areas of Japan, data retrieved from 21,128 participants
Inclusion criteria: aged 40‐79 years, from the Aichi Cancer Center Hospital (ACCH) in Aichi Prefecture, Japan
Recruitment: from January 1988‐June 1991
Interventions N/A
Outcomes Number of cases
Oesophageal cancer: 185 (male/female: 161/24) cases
Stomach cancer: 893 (male/female: 613/280) cases
Colon cancer: 362 (male/female: 213/149) cases
Rectal cancer: 266 (male/female: 173/93) cases
Green tea in exposure categories Exposure assessment: intake of green tea
Lowest exposure: rarely
Intermediate exposure 1: occasional
Intermediate exposure 2: 1‐2 cups/d
Intermediate exposure 3: 4‐6 cups/d
Highest exposure: ≥ 7 cups/d
Notes Funding: Grant‐in‐Aid for Cancer Research (9‐4) from the Ministry of Health and Welfare, Japan and a grant from the Foundation of All Japan Coffee Association
Statistical methods: unconditional logistic regression
Variables controlled in analysis: coffee intake, black tea intake, sex, age, year and season at 1st hospital visit, habitual smoking, habitual alcohol drinking, regular physical exercise, fruit intake, rice intake and beef intake
Variables controlled by matching: ‐
Data on Aichi also reported in Inoue 2009a for stomach cancer