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. 2020 Mar 2;2020(3):CD005004. doi: 10.1002/14651858.CD005004.pub3

Iwasaki 2014.

Study characteristics
Methods HCC in Japan
Participants Participants: 405 cases and 405 controls (all women)
Inclusion criteria: female, newly diagnosed and histologically confirmed breast cancer cases at 4 hospitals of Nagano prefecture, Japan
Recruitment: from May 2001‐September 2005
Interventions N/A
Outcomes Number of cases
Breast cancer: 369/405 eligible cases due to missing information on green tea, SNP genotype information, or DNA sample. Major histologic types were invasive ductal carcinoma (85.6%), invasive lobular carcinoma (4.1%) and mucinous carcinoma (3.8%).
Green tea in exposure categories Exposure assessment: green tea intake
Lowest exposure: 1‐119 mL/d
Intermediate exposure: 120‐599 mL/d
Highest exposure: ≥ 600 mL/d
Notes Funding: Grants‐in‐Aid for Research on Risk of Chemical Substances and the Third‐Term Comprehensive Ten‐Year Strategy for Cancer Control from the Ministry of Health, Labour and Welfare of Japan and Grants‐in‐Aid for Scientific Research on Innovative Areas (221S0001) and for Young Scientists (B) (22700934) from the Ministry of Education, Culture, Sports, Science and Technology of Japan and the Japan Society for the Promotion of Science and Foundation for Promotion of Cancer Research in Japan.
Statistical methods: conditional logistic regression
Variables controlled in analysis: menopausal status, number of births, family history of breast cancer, smoking status, moderate physical activity in the past 5 years, vitamin supplement use, oolong tea consumption, black tea consumption, coffee consumption and canned coffee consumption
Variables controlled by matching: sex, age (± 3 years) and residential area