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. 2020 Mar 2;2020(3):CD005004. doi: 10.1002/14651858.CD005004.pub3

Key 1999.

Study characteristics
Methods Cohort study in Japan
Participants Participants: 34,759 women from Hiroshima and Nagasaki
Inclusion criteria: women (93,741) present in Hiroshima and Nagasaki at the time of the bombings and city residents on 1 October 1950 and residents (23,580) not present at the time of the bombings but present between 1950 and 1953. Data of women recruited in the 1st and 2nd mail surveys, alive on 1 September 1969 (survey 1) and alive in September 1979 (Hiroshima) and July 1979 (Nagasaki)
Parental cohort: Radiation Effects Research Fundation's Life Span Study: final population of 34,765 women
Recruitment: 1969‐1970 (survey 1) and 1979 (survey 2)
Interventions N/A
Outcomes Number of cases
Outcome assessment: 31 December 1993
Breast cancer: 405/427 eligible cases (22 cases excluded due to missing data on green tea intake)
Green tea in exposure categories Exposure assessment: hot green tea intake
Lowest exposure: ≤ 1 time/d
Intermediate exposure: 2‐4 times/d
Highest exposure: ≥ 5 times/d
Notes Funding: research performed at the Radiation Effects Research Foundation (RERF), Hiroshima and Nagasaki, Japan. RERF is funded equally by the Japanese Ministry of Health and Welfare and the USA Department of Energy (DOE) Department of Energy through the National Academy of Sciences, Japan
Statistical methods: Poisson regression
Variables controlled in analysis: age, calendar period, city, age at the time of the bombing and radiation dose
Variables controlled by matching: ‐