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. 2020 Mar 2;2020(3):CD005004. doi: 10.1002/14651858.CD005004.pub3

Takezaki 2000.

Study characteristics
Methods HCC in Japan
Participants Participants: 127,477 inhabitants of 45 areas of Japan, data retrieved from 66,885 participants: 346 cases and 11,936 controls (all male) included in the present study
Inclusion criteria: aged 40‐79 years, from the Aichi Cancer Center Hospital (ACCH) in Aichi Prefecture, Japan.
Recruitment: from January 1988‐1997
Interventions N/A
Outcomes Number of cases
Pharynx (hypopharynx) cancer: 62 (male/female: NR) cases
Oesophageal cancer: 284 cases, including 53, 159 and 72 cases in upper, middle and lower third of the oesophagus
Green tea in exposure categories Exposure assessment: green tea drinking
Lowest exposure: occasionally or less
Intermediate exposure: 1‐6 cups/d
Highest exposure: ≥ 7 cups/d
Notes Funding: Grant‐in‐Aid for Cancer Research and the Comprehensive 10‐year Strategy for Cancer Control from the Ministry of Health and Welfare of Japan
Statistical methods: unconditional logistic regression
Variables controlled in analysis: age, year and season of visit, smoking and alcohol drinking
Variables controlled by matching: ‐