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. 2020 Mar 2;2020(3):CD005004. doi: 10.1002/14651858.CD005004.pub3

Ui 2009.

Study characteristics
Methods Cohort study in Japan
Participants Participants: 52,029 participants. Final data on 41,761 (male/female: 19,749/22,012) participants included
Inclusion criteria: aged 40‐79 years, living in 14 municipalities of Miyagi Prefecture in the catchment area of the Ohsaki Public Health Centre, Miyagi, Japan
Parent cohort: Ohsaki Cohort Study
Recruitment: from October‐December 1994
Data on the same cohort also reported in Kuriyama 2006 and Naganuma 2009.
Interventions N/A
Outcomes Number of cases
Outcome assessment: 31 December 2002
Liver cancer: 247 (male/female: 164/83) cases
Green tea in exposure categories Exposure assessment: green tea consumption
Lowest exposure: < 1 cup/d
Intermediate exposure 1: 1‐2 cups/d
Intermediate exposure 2: 3‐4 cups/d
Highest exposure: ≥ 5 cups/d
Notes Funding: Grant‐in‐Aid for Cancer Research and for the Third Term Comprehensive Ten‐Year Strategy for Cancer Control (H18‐3jigan‐ippan‐001), Ministry of Health, Labour and Welfare, in Japan
Statistical methods: Cox proportional hazard regression
Variables controlled in analysis: age, sex, alcohol consumption, smoking status, coffee consumption, vegetable consumption, dairy products consumption, fruit consumption, fish consumption and soybean consumption
Variables controlled by matching: ‐