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. 2020 Mar 2;2020(3):CD009628. doi: 10.1002/14651858.CD009628.pub2
Diagnostic category Biomarker probability of AD aetiology Aβ (PET or CSF) Neuronal injury (tau, FDG, sMRI)
MCI‐core clinical criteria Uninformative Conflicting/indeterminant/untested Conflicting/indeterminant/untested
MCI due to AD –
intermediate likelihood
Intermediate Positive Untested
MCI due to AD –
high likelihood
Highest Untested
Positive
Positive
Positive
MCI – unlikely due to AD Lowest Negative Negative
Aβ: amyloid beta peptide; AD: Alzheimer's disease; CSF: cerebrospinal fluid; FDG: fluorodeoxyglucose; MCI: mild cognitive impairment; sMRI: structural magnetic resonance imaging; PET: positron emission tomography