7. Clinical and psychological variables part 4.

Characteristics of study			Associated factors
Study ID	Tumour type	Dependent factor	Hearing problems	Vision impairments	Digestive problems	Musculoskeletal/neurological problems	Psychiatric comorbidity
Meeske 2005	ALL	Moderate to severe fatigue	NS (OR = 1.20)	NS (OR = 1.21)	‐	‐	‐
Puhr 2019	CNS	Severe fatigue	‐	‐	‐	‐	NS (no further information)
Rueegg 2013	Mix	Fatigued	Sa (OR = 2.85)	Sa (OR = 1.87)	Sa (OR = 3.15)	Sa (OR = 2.03)	‐

Clinical and psychological variables associated with fatigue. Presented results are from univariable analyses, unless multivariable analyses were available. In that case, we present only the results of the multivariable analyses in this table. More detailed information about the effect estimates can be found in the Characteristics of included studies tables.

ALL: acute lymphoblastoma leukaemia; CNS: central nervous system tumour; Mix: covering a broad range of childhood cancer diagnoses; NS: non‐significant; S: significant; OR: odds ratio

^aresults of multivariable analyses.