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. 2020 Mar 3;2020(3):CD012681. doi: 10.1002/14651858.CD012681.pub2

Meeske 2004.

Methods Study design: cross‐sectional study
Instrument used to assess fatigue: Pediatric Quality of Life Multidimensional Fatigue Scale parent‐proxy
Validated questionnaire: yes
Cut‐off score or criterion for severe fatigue: NAa
Time points at which outcome data were collected: NA, cross‐sectional study
Inclusion criteria: English‐ or Spanish‐speaking parents of children ages 2 ‐ 18 years with a diagnosis of brain tumour or ALL
Exclusion criteria: families whose children were recently diagnosed (< 6 weeks ago), families in medical crisis
Participants Sample characteristics:
N of participants original cohort: unknown; N of participants described study group: 256; N of participants study group of interest: 103; N of participants fatigue assessed: 103b
Participant characteristics:
Tumour type: ALL n = 53, brain tumour n = 50
Tumour stage: nm
Age at diagnosis: nm, based on age at assessment, the maximum age at diagnosis is 18 years
Time since end of therapy: no treatment for < 12 months n = 52, no treatment for at least 12 months n = 51
Age at assessment: nm, max 18 years
F/M: nm
BMI: nm
Race/ethnicity: nm
Marital status: NA
Highest completed education level: nm
Employment: NA
Physical activity level: nm
Sleeping problems: nm
Psychosocial problems: nm
 Comorbidities: nm
Genetic factors/mutations: nm
Interventions N of participants surgery: nm
N of participants chemotherapy: nm
N of participants radiotherapy: nm
Outcomes Severe fatigue:
N of participants with severe fatigue: NDa
Risk and associated factors:
no analysis performed with fatigue as outcome
Notes Funding sources: Supported by the Kellerman Foundation
Declaration of interest: nm
NA: not applicable; ND: no data available
aAuthors report fatigue on a continuous scale. Additional information on severe fatigue was requested and not available.
bOnly data of the participants off treatment were extracted