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. 2020 Mar 3;2020(3):CD012681. doi: 10.1002/14651858.CD012681.pub2

Robert 2012.

Methods Study design: cross‐sectional study
Instrument used to assess fatigue: PedsQL Multidimensional Fatigue Scale
Validated questionnaire: yes
Cut‐off score or criterion for severe fatigue: NAa
Time points at which outcome data were collected: NA, cross‐sectional study
Inclusion criteria: English‐ or Spanish‐speaking survivor of childhood cancer, > 2 years after treatment, participating in MD Anderson Survivorship Clinic, at least 25 years of age, completed adapted versions of the PedsQL
Exclusion criteria: cognitive impairment
Participants Sample characteristics:
N of participants original cohort: unknown; N of participants described study group: 64; N of participants study group of interest: 64; N of participants fatigue assessed: 64
Participant characteristics:
Tumour type: CNS tumour n = 9, haematological/leukaemia n = 11, lymphoma n = 11, solid tumour n = 33
Tumour stage: nm
Age at diagnosis: mean 9.6 years (SD 5.3; range 1 ‐ 21)b
Time since diagnosis: mean 25.2 years (SD 9.3; range 5 ‐ 43)
Age at assessment: mean 34.5 years (SD7.4; range 25 ‐ 53)
F/M: 38/26
BMI: nm
Race/ethnicity: Asian n = 2, black n = 5, Hispanic n = 15, white n = 42
Marital status: nm
Highest completed education level: nm
Employment: nm
Physical activity level: PedsQL physical health subscale mean 73.8 (SD 25.0)
Sleeping problems: nm
Psychosocial problems: nm
 Comorbidities: nm
Genetic factors/mutations: nm
Interventions N of participants surgery: nm
N of participants chemotherapy: nm
N of participants radiotherapy: nm
Outcomes Severe fatigue:
N of participants with severe fatigue: NDa
Risk and associated factors:
no analysis performed with fatigue as outcome
Notes Funding sources: supported by the Astros’ Baseball Team Long‐Term Survivor Fund and the National Institutes of Health through MD Anderson’s Cancer Center Support Grant CA016672
Declaration of interest: Nothing to report
aAuthors report fatigue on continuous scale. Additional information on severe fatigue was requested and not available.
bInformation received from the study author: 62 of the 64 participants (96%) were under 18 at diagnosis.