Table 1.

Characteristics of Study Population at Baseline and After 3 to 6 Months of Medical Weight Loss by Glucose Tolerance Category

	Normal Weight	Obese (N = 58)
	NFG	NFG		IFG		T2DM		Total
	Baseline	Baseline	3-6 Mos	Baseline	3-6 Mos	Baseline	3-6 Mos	Baseline	3-6 Mos
Number	13	14	14	24	24	20	20	58	58
Age, years	45 ± 11	45 ± 9	──	51 ± 4	──	50 ± 6	──	49 ± 7	──
Sex	8F/5M	7F/7 M	──	9F/15M	──	11F/9M	──	27F/31M	──
Race/ethnicity	1B/12W	1B/13W	──	2B/22W	──	1A/2B/17W	──	1A/5B/52W	──
Duration of diabetes, years	──	──	──	──	──	3 ± 3	──	──	──
Weight, kg	65 ± 11	120 ± 12	98 ± 10**	118 ± 23	99 ± 18**	116 ± 19	96 ± 15**	117 ± 19	97 ± 15**
BMI, kg/m2	23 ± 2	39 ± 4	32 ± 3**	40 ± 5	33 ± 4**	40 ± 5	33 ± 4**	39 ± 4	33 ± 4**
Fasting glucose, mg/dL	94 ± 10	92 ± 6	88 ± 11	110 ± 7	100 ± 14**	123 ± 17	99 ± 9**	110 ± 16	97 ± 12*
Glucose AUC, min·mg/dL	7009 ± 797	6634 ± 661	6242 ± 840	7832 ± 911	7094 ± 862*	9094 ± 1666	7463 ± 1074**	7978 ± 1500	7015 ± 1032**
Fasting insulin, μIU/mL	10 ± 2	21 ± 6	13 ± 4**	27 ± 8	16 ± 5**	31 ± 12	16 ± 6**	27 ± 10	15 ± 5**

Values given as mean ± standard deviation.

Abbreviations: A, Asian, AUC, area under the curve between 0 and 60 minutes; B, black; BMI, body mass index; F, female; IFG, impaired fasting glucose; M, male; mos, months; NFG, normal fasting glucose; T2DM, type 2 diabetes; W, white.

*P < 0.05 post (3–6 mos) vs pre within group (Wilcoxon test for paired observations)

**P < 0.005 post (3–6 mos) vs pre within group (Wilcoxon test for paired observations)