Table 2. Diffusion rates and percent occupancy of KRAS4b in cancer cell lines.
Dataset KRAS4b |
Diffusion coefficient (µm2/s) | Occupancy (%) | ||||
---|---|---|---|---|---|---|
D1 | D2 | D3 | F1 | F2 | F3 | |
HeLa (KRAS4b WT) |
0.95 ± 0.03 | 0.24 ± 0.03 | 0.06 ± 0.01 | 64 ± 2 | 22 ± 2 | 14 ± 3 |
MEF (KRAS4b WT) |
0.73 ± 0.12 | 0.25 ± 0.09 | 0.05 ± 0.01 | 42 ± 9 | 30 ± 8 | 28 ± 2 |
PANC-1 (KRAS4b G12D) |
0.84 ± 0.06 | 0.22 ± 0.01 | 0.04 ± 0.01 | 43 ± 6 | 40 ± 4 | 17 ± 2 |
SU.86.86 (KRAS4b G12D) |
0.8 ± 0.16 | 0.18 ± 0.09 | 0.02 ± 0.01 | 66 ± 14 | 28 ± 9 | 6 ± 5 |
hTERT-HPNE (KRAS4b G12D) |
0.92 ± 0.06 | 0.25 ± 0.02 | 0.06 ± 0.01 | 55 ± 3 | 29 ± 1 | 16 ± 3 |