Table 5. Diffusion rates and percent occupancy in full length KRAS4b, the HVR, and HVR mutants in HeLa cells.
Dataset HeLa |
Diffusion coefficient (µm2/s) | Occupancy (%) | ||||
---|---|---|---|---|---|---|
D1 | D2 | D3 | F1 | F2 | F3 | |
KRAS4b | 0.95 ± 0.06 | 0.24 ± 0.03 | 0.06 ± 0.01 | 66 ± 2 | 23 ± 2 | 14 ± 3 |
4bHVR | 0.98 ± 0.03 | 0.17 ± 0.03 | 87 ± 5 | 13 ± 5 | ||
4bHVR-3A | 1.08 ± 0.06 | 0.13 ± 0.04 | 87 ± 6 | 13 ± 5 | ||
4bHVR-5A | 1.07 ± 0.04 | 0.15 ± 0.02 | 82 ± 8 | 18 ± 6 | ||
4bHVR-5Ea | 1.21 ± 0.05 | 0.15 ± 0.05 | 87 ± 3 | 13 ± 4 | ||
4bHVR-5Eb | N/A | N/A | N/A | N/A | N/A | N/A |