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α-Parvalbumins show lower capacity than β-parvalbumins to induce skin reactions in patients allergic to fish. SPTs were performed with different doses of natural purified fish parvalbumins. Parvalbumins were used in concentrations ranging from 0.1 μg/mL to 50 μg/mL. Average wheal diameter of greater than or equal to 3 mm compared with negative control was rated as a positive response. (X) indicates that SPT was not performed.
