Table 4:

Associations of AMH, FSH and Inhibin B with ovarian cancer by tumor characteristic

Type 1				Type 2
Excluding subtypes designated “other”
FSH§	Cases (N=53)	Control (N=53)	Conditional Adjusted OR* (95% CI)		Cases (n=50)	Control (N= 50)	Conditional Adjusted OR* (95% CI)
Median
Below median < 0.77	26 (49)	26 (49)	1.0 (ref)	Below median < 0.76	21 (42)	30 (60)	1.0 (ref)
Above median > 0.77	27 (51)	27 (51)	1.09 (0.45–2.65)	Above median > 0.76	29 (58)	20 (40)	2.78 (1.05–7.38)
Inhibin B
LOD split
Undetectable < 1.11	25 (47)	32 (60)	1.0 (ref)	Undetectable < 1.32	22 (44)	28 (56)	1.0 (ref)
Detectable > 1.11	28 (53)	21 (40)	3.06 (1.03–9.07)	Detectable > 1.32	28 (56)	22 (44)	1.80 (0.75–4.37)
Excluding tumors of unknown grade
FSH	Cases (N=54)‡	Control (N=54)	Conditional Adjusted OR* (95% CI)		Cases (n=60)	Control (N= 60)	Conditional Adjusted OR* (95% CI)
Median
Below median < 0.76	26 (48)	27 (50)	1.0 (ref)	Below median < 0.76	20 (33)	30 (50)	1.0 (ref)
Above median > 0.76	28 (52)	27 (50)	1.12 (0.47–2.71)	Above median > 0.76	40 (67)	30 (50)	2.74 (1.04–7.21)
Inhibin B
LOD Split
Undetectable < 1.11	25 (46)	32 (60)	1.0 (ref)	Undetectable < 1.11	22 (37)	33 (66)	1.0 (ref)
Detectable > 1.11	29 (54)	22 (40)	3.10 (1.04–9.23)	Detectable > 1.11	38 (63)	27 (54)	1.89 (0.87–4.12)

Abbreviation: OR, odds ratio; Q, quartile; ref, reference group; MV, multivariable; LOD, level of detection

^*Conditional on matching variables (age at blood draw and birthyear) and adjusted for parity

^†Test of trend using the Wald statistic from ordinal regression over quartile/group

^‡All endometrioid, mucinous and clear cell tumors are categorized as Type 1 independent of grade.

^§All analytes were log transformed