Figure 4. Effects of in vivo hypoxia on the expression of ET-1 receptors in the murine placenta.
A) ET-1 receptor A protein expression is higher in hypoxic (HX) compared to normoxic (NORM) mouse placental homogenates. B) ET-1 receptor B protein expression is unaffected by HX. C) Representative immunohistochemical staining of placentas from NORM (i and ii) and HX (iii and iv) mice reveal qualitatively higher expression of both ET-1 receptors A and B with HX. N = 6 NORM, 6 HX dams for each receptor in placenta.