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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2020 Mar;75(3):211–221. doi: 10.1097/FJC.0000000000000778

Fig.2.

Fig.2.

SDX-induced concentration-dependent vein contraction. Rat IVC rings were pre-contracted with submaximal Phe concentration (6×10−7M). Increasing concentrations of SDX (0.001–1mg/ml) or equal volumes of the vehicle Krebs were added and the effects on IVC contraction in milligrams (mg) were measured (A). To correct for variability in the vein segment size and its responsiveness to vasoconstrictors, the SDX-induced contraction was normalized and presented in mg/mg tissue weight (B), as % of initial Phe pre-contraction (C), and as % of control 96mM-KCl contraction (D). Data represent means±SEM, n=6. * Significantly different (P<0.05) versus vehicle.