Table 3.

Cox proportional hazards regression for TTR, for predictor variables

TTR		Unadjusted				Adjusted
Factor	Level	HR	CI-	CI+	p	HR	CI-	CI+	p
Side	Right	(Ref)				(Ref)
	Left	0.7	0.4	1.1	0.088	0.5	0.3	0.9	0.016
pT	pT1–2	(Ref)			0.002	(Ref)			0.898
pT3	a	2.7	0.8	9.2	0.115	1.6	0.4	5.9	0.469
	b	2.9	1.0	8.8	0.053	1.6	0.5	5.0	0.454
	c	4.1	1.4	12.4	0.011	1.5	0.4	4.8	0.534
	d	6.9	2.2	21.5	0.001	2.3	0.7	8.1	0.181
pT4	a	8.0	2.7	23.9	< 0.001	2.1	0.6	7.2	0.235
	b	6.3	1.8	21.4	0.003	1.9	0.5	7.0	0.357
pN	0	(Ref)			< 0.001	(Ref)			< 0.001
	1a	3.4	1.7	6.8	0.001	2.6	1.2	5.7	0.013
	1b	2.8	1.4	5.7	0.005	2.3	1.0	5.1	0.044
	1c	1.7	0.4	7.3	0.470	1.5	0.3	6.9	0.600
	2a	6.5	3.4	12.5	< 0.001	5.4	2.4	12.0	< 0.001
	2b	9.3	4.8	18.0	< 0.001	6.4	2.8	14.9	< 0.001
LNR	0–1	37.2	15.6	88.6	< 0.001	3.6	0.7	18.0	0.119
TD	No	(Ref)				(Ref)
	Yes	2.2	1.3	3.8	0.004	0.8	0.4	1.5	0.437
CEA	ng/ml
Preoperative	< 5	(Ref)				(Ref)
	> 5	1.7	1.0	2.8	0.063	1.2	0.7	2.2	0.464
Postoperative	< 5	(Ref)				(Ref)
	> 5	3.9	2.0	7.6	< 0.001	2.6	1.2	5.6	0.018
CRP	mg/l
Preoperative	< 10	(Ref)				(Ref)
	> 10	1.9	1.2	3.0	0.008	1.0	0.6	1.7	0.994
Postoperative	< 10	(Ref)				(Ref)
	> 10	1.8	1.0	3.5	0.067	1.8	0.9	3.9	0.108

Variables tested one by one (unadjusted), and with the baseline model (adjusted)

HR hazard ratio; CI confidence interval, with lower and upper bounds reported; LNR lymph node ratio (positive nodes by found nodes)