Table 1.
Physicochemical parameters of peptides
| Tn CRT2 | Tn CRT3 | |
|---|---|---|
| Sequence | RKGSRMGKKCECP | RKGSQMGKKCECP |
| Molecular weight | 1478.83 g/mol | 1450.77 g/mol |
| Net charge at pH7 | + 3.9 | + 2.9 |
| Theoretical isoelectric point (pI) | 9.85 | 9.39 |
| GRAVY (grand average of hydropathicity)a | − 1.577 | − 1.500 |
| Instability indexb | 59.60 | 59.60 |
| Boman Index (kcal/mol) | 3.83 | 3.11 |
| Hydrophobicity | + 25.74 kcal mol−1 | + 24.70 kcal mol−1 |
Physicochemical parameters were obtained using the ProtParam tool in ExPASy (Gasteiger et al. 2003) (https://web.expasy.org/protparam/; accessed on 18 February 2019)
aThe negative GRAVY value suggests that this peptide is hydrophilic
bThe instability index value indicates that this peptide is unstable