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. 2020 Mar 6;10:17. doi: 10.1186/s13550-020-0598-2

Table 1.

Patient characteristics, history of prostate cancer and outcome from lymphadenectomies from 23 patients undergoing lymphadenectomy

Parameters Values
iPSA at primary therapy (ng/ml)
 Mean ± SD/median/range 10.79 ± 7.5/8.8/3.37–37.0
Primary therapy, n
 Radical prostatectomy 21/23 (91.3%)
 Radiotherapy 2/23 (8.7%)
Gleason score, n
 7a 4 (17%)
 7b 7 (31%)
 8 5 (22%)
 9 7 (30%)
111In-PSMA-guided LA overall, n
 Primary 2/23 (8.7%)
 Salvage lymph node dissection 21/23 (91.3%)
Age at lymphadenectomy (years)
 Mean ± SD/median/range 67.5 ± 6.6/67/52–78
PSA at 111In-PSMA-guided LA (ng/ml)
 Mean ± SD/median/range 7.9 ± 12.9/1.8/0.03–56.2
Time between PET/CT and 111In-PSMA-guided LA (months)
 Mean ± SD/median/range 3.2 ± 1.6/3.0/1.0–8.0
Time between primary therapy and 111In-PSMA-guided LA (years) (n = 21)
 Mean ± SD/median/range 4.9 ± 3.7/4.4/1.5–13.7
Histological outcome for 23 patients, n
 LA with positive histology 21/23 (91.3%)
 LA with negative histology 2/23 (8.7%)
Topography of 111In-PSMA-guided LA in 23 patients, n
 Pelvic right and left 13/23 (57%)
 Pelvic left only 2/23 (9%)
 Pelvic right only 1/23 (4%)
 Pelvic right and left and retroperitoneal 7/23 (30%)
Topography of subregions with confirmed PCa, n
 Pelvic left, n 38/275 (37%)
 Pelvic right, n 41/275 (40%)
 Retroperitoneal 24/275 (23%)
Histological outcome for 275 subregions with 275 samples, n
 Subregions/samples with LNM 104/275 (37.5%)
 Subregions/samples without LNM 171/275 (62.5%)
 Subregions/samples with additional non-nodal PCa-tissue 7/104 (5.8%)
Number of LN removed (n)
 Overall 864
 Per patient (mean ± SD/median/range) 37.6 ± 17.2/38.0/2.0–82.0
Number of LNM removed (n)
 Overall 197
 Per patient (mean ± SD/median/range) 8.6 ± 14.9/4.0/0.0–71.0
LNM fraction per patient (LNM×100/LN = %)
 Mean ± SD/median/range 20.9 ± 24.4/12.5/0.0–87.1

LNM lymph node metastases, LN lymph node, PSA prostate-specific antigen, LA lymphadenectomy