Table 2.

Table showing the primer sets used to assess the presence of single nucleotide polymorphisms within the genes GDF5 (variant rs143383), SMAD3 (rs12901499), IL1-R1 (variant rs2287047) AND A2BP1 (variant rs716508).

Gene	SNP	Primer Forward (5′-3′)	Primer Reverse (5′-3′)	Size
GDF5	rs143383	caggcctgtgagtgtgtgtg	cagcagtagcagcagaagga	376 bp
SMAD3	rs12901499	ttaaagcaggggagtggcac	aagcacaggcccccaaatta	368 bp
ALDH1A2	rs3204689	ctcttccaaggagatgtcagc	acacacacaccccaaaactg	332 bp
IL1-R1	rs2287047	accagcctccagagaagaaa	gtgcatagctgactttggatgt	411 bp

GDF5 (growth differentiation factor 5); SMAD3 (SMAD family member 3); ALDH1A2 (aldehyde dehydrogenase 1 family A2); IL1-R1 (interleukine 1 receptor 1); SNP (single nucleotide polymorphism); bp (base pair).