Table 3.
. Effect of HM01 (10 mg·kg−1, p.o.) and HM02 (30 mg·kg−1, p.o.) on spontaneous behaviours in Suncus murinus
| Spontaneous behaviour before motion (60 min) | Spontaneous behaviour after motion (60 min) | |||||
|---|---|---|---|---|---|---|
| Vehicle + Motion | HM01 + Motion | HM02 + Motion | Vehicle + Motion | HM01 + Motion | HM02 + Motion | |
| Exploring | 14.2 ± 3.2 | 9.7 ± 2.4 | 10.7 ± 3.5 | 1.7 ± 0.7 | 1.8 ± 0.8 | 13.0 ± 8.2 |
| Face washing | 1.5 ± 0.6 | 0.0 ± 0.0 | 0.0 ± 0.0 | 2.0 ± 1.6 | 0.0 ± 0.0 | 0.8 ± 0.7 |
| Chin on the floor | 9.7 ± 3.2 | 6.8 ± 1.4 | 12.8 ± 7.5 | 6.7 ± 2.6 | 1.3 ± 0.7 | 2.3 ± 1.9 |
| Scratching | 16.7 ± 6.8 | 2.8 ± 1.9 | 4.5 ± 3.0 | 36.8 ± 14.3# | 5.7 ± 3.9* | 3.5 ± 2.7* |
| Sniffing | 22.2 ± 4.4 | 26.0 ± 3.7 | 30.8 ± 3.5 | 12.0 ± 5.0 | 9.2 ± 2.5# | 12.7 ± 3.7# |
| Licking | 7.7 ± 3.3 | 4.5 ± 3.1 | 2.8 ± 1.6 | 13.5 ± 5.1 | 4.6 ± 3.7 | 2.0 ± 0.9 |
| Resting | 42.0 ± 3.0 | 45.9 ± 2.2 | 43.5 ± 2.5 | 44.9 ± 4.4 | 53.4 ± 2.8 | 49.6 ± 4.2 |
Note. Resting is calculated in minutes; other behaviours are calculated in episodes. Data represent the mean ± SEM of six animals.
P < .05, for inter‐group comparison, significantly different from Vehicle + Motion group.
P < .05, significantly different, referring to intra‐group comparison; two‐way ANOVA followed by Bonferroni tests.