Figure 3.

Effect of intra‐VTA microinjections of LY2817412 on voluntary alcohol drinking in male and female msP rats. Male (n = 9) and female (n = 8) msP rats were implanted with bilateral cannulas in the VTA and then subjected to a two‐bottle free‐choice test. Following treatment with LY2817412 (3 and 6 μg·μl⁻¹ per rat) or vehicle, the voluntary intake of (a) alcohol, (b) water, and (c) food was recorded 2 hr after drinking onset in both male and female msP rats. The data are expressed as mean ± SEM. ^* P < .05, significantly different from vehicle; two‐way ANOVA followed by Newman–Keuls post hoc test