Table 1.
BP and heart rate in insulin‐resistant and insulin‐deficient AnxA1 +/+ and AnxA1 −/− male mice
| Insulin‐resistant study | Insulin‐deficient study | |||||||
|---|---|---|---|---|---|---|---|---|
| Sham | Insulin resistant | Sham | Insulin deficient | |||||
| AnxA1 +/+ | AnxA1 −/− | AnxA1 +/+ | AnxA1 −/− | AnxA1 +/+ | AnxA1 −/− | AnxA1 +/+ | AnxA1 −/− | |
| SBP (mmHg) | 97 ± 2 (10) | 107 ± 6 (6) | 107 ± 6 (5) | 123 ± 5 (13) | 117 ± 6 (8) | 116 ± 5 (7) | 93 ± 3 * (5) | 95 ± 5 * (5) |
| DBP (mmHg) | 66 ± 2 (10) | 70 ± 4 (6) | 68 ± 7 (5) | 81 ± 3 (13) | 74 ± 4 (8) | 79 ± 4 (7) | 63 ± 2 (5) | 63 ± 7 (5) |
| HR (BPM) | 409 ± 4 (10) | 401 ± 10 (6) | 404 ± 13 (5) | 446 ± 14 # (13) | 401 ± 8 (8) | 404 ± 13 (7) | 399 ± 20 (5) | 412 ± 19 (5) |
Note. Values are mean ± SEM with n indicated in parentheses. Data were analysed using two‐way ANOVA with Fisher's LSD post hoc analysis.
Abbreviations: SBP, systolic BP; DBP, diastolic BP; HR, heart rate.
*
P < .05, significantly different from sham AnxA1 +/+.
#
P < .05, significantly different from sham AnxA1 +/+.