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. 2020 Feb 8;111(3):940–950. doi: 10.1111/cas.14300

Figure 2.

Figure 2

ZR30 inhibits angiogenesis in vivo. A, Representative pictures of Matrigel plugs removed from mice 1 week after s.c. injection from negative control (G1), positive control (G2), and ZR30 treatment (G4) groups of mice. B, Representative pictures of Masson’s trichrome stained sections of Matrigel plugs. C, Comparison of vessel density in 4 groups of Matrigel plugs. Columns, mean (n = 3); bars, SD. *P < .05; **P < .005. D, Masson’s trichrome and CD31 immunohistochemistry (IHC) of Matrigel plugs containing VEGF‐165 (100 ng/mL) and basic fibroblast growth factor (bFGF, 300 ng/mL), with or without ZR30 (100 or 300 ng/mL)