Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IC50 values for neratinib and the methods of drug exposure in neratinib‐resistant cell lines
| Cancer type | Cell line | Method of drug exposure |
Neratinib IC50 Mean ± standard error (μmol/L) |
|---|---|---|---|
| Breast | BT‐474 | — | 0.0028 ± 0.00019 |
| BT‐474‐NRS | Stepwise | 0.97 ± 0.18 | |
| BT‐474‐NRS2 | Stepwise | 1.45 ± 0.25 | |
| BT‐474‐NRH | High | 1.69 ± 0.35 | |
| BT‐474‐NRH2 | High | 1.44 ± 0.26 | |
| Lung | H2170 | — | 0.029 ± 0.0059 |
| H2170‐NRS | Stepwise | >10 | |
| H2170‐NRH | High | 3.96 ± 0.49 |
‐, not applicable.
