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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Pharmacol Res. 2019 Dec 23;152:104589. doi: 10.1016/j.phrs.2019.104589

Table 5.

Significantly overrepresented biological processes in RIS hearts.

Overrepresentation test PANTHER GO-Slim Biological Process # of proteins Fold Enrichment p-value FDR
small molecule metabolic process (GO:0044281) 6 8.61 8.91E-05 3.97E-02
carboxylic acid metabolic process (GO:0019752) 8 6.61 3.63E-05 3.23E-02
oxoacid metabolic process (GO:0043436) 8 6.35 4.78E-05 2.84E-02
organic acid metabolic process (GO:0006082) 8 5.45 1.35E-04 4.81E-02
cellular metabolic process (GO:0044237) 24 3.18 4.25E-07 7.58E-04

Using PANTHER analysis, all 5 of the significantly overrepresented biological processes identified were related to metabolic process identified by gene ontology (GO) terms. Fisher test, False Discovery Rate, FDR <0.05