Table 1.
Association between (P) RR expression levels in primary colorectal tumors and clinicopathological characteristics
| Case number | (P) RR expression level (Immunohistochemistry) | Constituent ratio difference |
||||
|---|---|---|---|---|---|---|
| Weak | Middle | Strong | Pvalue | χ2 | ||
| Case number (percentage) | ||||||
| Gender | 60 | |||||
| Male | 31 | 4 (12%) | 15 (47%) | 13 (41%) | < 0.0001*** | 27.36 |
| Female | 28 | 9 (32%) | 16 (57%) | 13 (11%) | ||
| Onset age | 60 | |||||
| <60 | 12 | 1 (8%) | 7 (59%) | 4 (33%) | 0.005** | 10.6 |
| ≥ 60 | 48 | 12 (25%) | 24 (50%) | 12 (25%) | ||
| WHO Grade of cancer differentiation | 60 | |||||
| Grade 1 | 17 | 5 (29%) | 11 (65%) | 1 (6%) | < 0.0001*** | 77.56 |
| Grade 2 | 30 | 7 (23%) | 16 (53%) | 7 (23%) | ||
| Grade 3 | 13 | 1 (8%) | 4 (31%) | 8 (61%) | ||
| UICC Stage | 60 | |||||
| Stage II | 20 | 9 (45%) | 8 (40%) | 3 (15%) | < 0.0001*** | 65.5 |
| Stage III | 20 | 3 (15%) | 13 (65%) | 4 (20%) | ||
| Stage IV | 20 | 1 (5%) | 10 (50%) | 9 (45%) | ||
| Distant Metastasis and/or Progression after radical operation | 60 | |||||
| No | 23 | 5 (22%) | 14 (61%) | 4 (17%) | 0.0352* | 6.695 |
| Yes | 37 | 8 (22%) | 17 (46%) | 12 (32%) | ||
| Five-year survival (patients who finished the 5-year follow-up or died within 5 years) | 47 | |||||
| Yes | 25 | 5 (20%) | 13 (52%) | 7 (28%) |
0.0358 * |
6.661 |
| No | 22 | 2 (9%) | 11 (50%) | 9 (41%) | ||
|
Recurrence-free survival time (duration from radical operation to recurrence) (months) (20 cases who had recurrence after radical operation) |
||||||
| (P) RR expression level | Pvalue | χ2 | Hazard radio | 95% CI | ||
|
Week/Middle (16 cases) |
Strong (4 cases) |
|||||
| 10.4 | 5.85 | 0.0064** | 7.438 | 0.06804 | 0.00986–0.4695 | |
UICC The Union for International Cancer Control