Fig. 6.

Differentially accessible regions linked to gene expression changes contain specific transcription factor binding motifs. a, b Transcription factor motifs gained (left) or lost (right) within open-chromatin regions that are linked to differentially expressed genes in LM2 (a) or BrM2 (b) compared to Par. Significant linkages were determined using HiChIP (see Methods). c Venn diagrams of TFs whose motifs are gained (left) or lost (right) in LM2 and BrM2