Table 3.
Items2 | Infused glucose, g/d | SEM | P-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|
0 | 20 | 40 | 60 | 80 | 100 | Linear | Quadratic | Cubic | ||
Essential AA, mmol/d | ||||||||||
Arg | 12.3 | 14.5 | 15.9 | 23.6 | 14.3 | 9.32 | 5.01 | 0.96 | 0.06 | 0.78 |
His | 10.2 | 8.18 | 12.7 | 17.2 | 17.4 | 7.20 | 5.24 | 0.81 | 0.22 | 0.15 |
Ile | 15.7 | 19.2 | 25.2 | 32.4 | 17.9 | 14.3 | 5.32 | 0.95 | 0.02 | 0.68 |
Leu | 16.7 | 21.4 | 27.2 | 31.8 | 21.1 | 19.5 | 4.13 | 0.32 | < 0.01 | 0.74 |
Lys | 11.8 | 13.5 | 22.9 | 26.9 | 17.7 | 14.2 | 1.86 | 0.39 | < 0.01 | 0.50 |
Met | 2.97 | 3.96 | 6.38 | 7.52 | 5.21 | 3.34 | 1.18 | 0.80 | < 0.01 | 0.92 |
Phe | 10.3 | 11.9 | 13.9 | 16.7 | 10.1 | 11.2 | 1.98 | 0.76 | 0.04 | 0.81 |
Thr | 11.2 | 15.4 | 16.7 | 18.8 | 15.1 | 13.4 | 2.29 | 0.57 | 0.02 | 0.28 |
Val | 16.1 | 16.7 | 20.5 | 24.6 | 20.8 | 15.9 | 2.21 | 0.39 | < 0.01 | 0.24 |
Non-essential AA, mmol/d | ||||||||||
Ala | 14.6 | 13.2 | 20.3 | 15.5 | 11.7 | 10.3 | 3.34 | 0.51 | 0.58 | 0.91 |
Asx | 2.88 | 1.42 | 2.05 | 2.04 | 4.41 | 1.52 | 0.87 | 0.99 | 0.74 | 0.13 |
Cys | 3.06 | 4.38 | 7.14 | 8.03 | 4.58 | 3.53 | 1.22 | 0.36 | < 0.01 | 0.64 |
Glx | 19.2 | 25.3 | 38.8 | 44.9 | 32.3 | 20.2 | 4.63 | 0.26 | < 0.01 | 0.90 |
Gly | 4.55 | 5.04 | 11.1 | 9.95 | 8.01 | 5.83 | 2.89 | 0.67 | 0.08 | 0.87 |
Pro | 9.20 | 11.5 | 13.6 | 11.9 | 14.2 | 9.3 | 4.55 | 0.69 | 0.25 | 0.25 |
Ser | 11.5 | 17.1 | 22.3 | 23.5 | 13.2 | 12.8 | 4.84 | 0.81 | 0.03 | 0.57 |
Tyr | 8.80 | 10.6 | 10.9 | 12.1 | 9.50 | 10.1 | 1.82 | 0.69 | 0.15 | 0.67 |
Essential AA, mmol/d | 107 | 125 | 161 | 200 | 140 | 108 | 23.2 | 0.49 | < 0.01 | 0.26 |
Non-essential AA, mmol/d | 73.8 | 88.5 | 126 | 128 | 97.9 | 73.6 | 14.2 | 0.58 | 0.04 | 0.62 |
Group-1 AA, mmol/d | 32.3 | 34.6 | 43.9 | 53.5 | 42.2 | 31.8 | 8.25 | 0.70 | 0.07 | 0.86 |
Group-2 AA, mmol/d | 83.8 | 100 | 128 | 158 | 107 | 86.6 | 19.9 | 0.65 | 0.01 | 0.50 |
Branched-chain AA, mmol/d | 48.5 | 57.3 | 72.9 | 88.8 | 59.8 | 49.7 | 10.1 | 0.70 | < 0.01 | 0.59 |
Total AA, mmol/d | 181 | 213 | 288 | 327 | 238 | 182 | 33.4 | 0.59 | < 0.01 | 0.45 |
1 Mammary gland uptake of AA (mmol/d) = (arterial − venous difference) (mmol/L) × mammary gland plasma flow (L/d)
2 Glx: glutamate + glutamine; Asx: aspartate + asparagines; Group-1 AA: His, Met, Phe, and Tyr; Group-2 AA: Arg, Ile, Leu, Lys, Thr, and Val; Branched-chain AA: Ile, Leu, and Val