Table 2.
Mortality by reperfusion status and reperfusion-mortality association
| Mortality | ||
|---|---|---|
| 30-day | 180-day | |
| 1. Mortality, n (%) | ||
| No reperfusion (n = 20,159) | 7959 (39.5) | 9105 (45.2) |
| PCI (n = 27,983) | 3600 (12.9) | 4649 (16.6) |
| TBL only (n = 16,405) | 3071 (18.7) | 3708 (22.6) |
| 2. Difference in mortalitya, % points (95% CI) | ||
| PCI vs. no reperfusion | −26.6* (−25.8, −27.4) | −28.6* (−27.7, −29.4) |
| TBL only vs. no reperfusion | −20.8* (−19.9, − 21.7) | −22.6* (− 21.6, − 23.5) |
| PCI vs. TBL only | −5.9* (−5.1, −6.6) | −6.0* (−5.2, −6.8) |
| 3. Difference in probability of dyingb, % points (95% CI) | ||
| PCI vs. no reperfusion | −19.6* (− 18.2, − 21.0) | −21.1* (− 19.6, − 22.5) |
| TBL only vs. no reperfusion | −14.1* (− 13.3, − 14.9) | −15.1* (−14.3, −16.0) |
| PCI vs. TBL only | −5.5* (− 2.7, −8.2) | −5.4** (− 2.4, −8.5) |
* P < 0.001; ** P < 0.01
a Crude analysis without any adjustment for baseline differences between treatment and control groups
b Average treatment effect on the treated (ATET), using PSM between treatment and control groups (See Additional file 1: Figures S4A, B, and C and Table S2 for the covariates predicting treatment probabilities); 95% CI based on robust standard error
CI confidence interval; n number of patients; PCI percutaneous coronary intervention; PSM propensity-score matching; TBL thrombolysis