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. 2020 Feb 18;117(9):4642–4652. doi: 10.1073/pnas.1919563117

Fig. 3.

Fig. 3.

Effects of BPA and BPS on the placental production of neurotransmitters and E2 at e12.5. (A) Both BPA and BPS increased placental dopamine concentrations. *P = 0.01; **P = 0.03. (B) Both EDCs reduced placental production of serotonin (5-HT). *P = 0.0001; **P = 0.0006. (C) The placental 5-HIAA:5-HT ratio was increased with both chemicals. *P = 0.0001; **P = 0.001. (D) Placental E2 concentrations were reduced in BPA vs. control group. N = 10 to 16 biological replicates per group. *P = 0.01.