Table 3.
Comparison of Lung Function Parameters Between COPD Patients with and Without PH
| COPD Patients Without PH | COPD Patients with PH | p-value | |
|---|---|---|---|
| N | 143 | 40 | |
| FEV1a | 1830 (1320–2250) | 1410 (912.5–1995.0) | <0.01 |
| %FEV1b | 68.1 ± 20.8 | 61.4 ± 24.2 | 0.09 |
| %DLCOb | 77.9 ± 25.1 | 61.6 ± 24.9 | <0.01 |
| %TLCb | 101.2 ± 14.7 | 98.8 ± 13.5 | 0.40 |
| %ICb | 117.3 ± 24.7 | 110.9 ± 24.4 | 0.20 |
| IC/TLCb | 0.43 ± 0.08 | 0.39 ± 0.07 | 0.02 |
| %RVa | 95.1 (82.4–112.8) | 101.1 (77.3–115.8) | 0.93 |
| RV/TLCa | 0.39 (0.32–0.45) | 0.34 (0.31–0.40) | 0.06 |
Notes: Data are presented as the mean ± SD or median (IQR). Data were compared between groups using athe Mann–Whitney U-test, or bthe Student’s t-test.
Abbreviations: COPD, chronic obstructive pulmonary disease; PH, pulmonary arterial hypertension; FEV1, forced expiratory volume in 1 second; %FEV1, forced expiratory volume in 1 second as a percentage of predicted forced expiratory volume in 1 second; DLCO, diffusing capacity of the lung for carbon monoxide; TLC, total lung capacity; IC, inspiratory capacity; RV, residual volume; SD, standard deviation; IQR, interquartile range.