Table 1.
Univariate and multivariate analysis of OS, DFI, PFI, and DSS in patients with PAAD in the TCGA.
| Parameters | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| p | HR | 95% (lower/upper) | p | HR | 95% (lower/upper) | |||
| OS | ||||||||
| Age >65 vs. ≤65 |
0.141 | 0.752 | 0.515 | 1.099 | ||||
| Female vs. male | 0.228 | 0.793 | 0.545 | 1.156 | ||||
| Smoking history 2/3/4/5 vs. 1 |
0.732 | 1.076 | 0.706 | 1.641 | ||||
| Alcohol history Yes vs. no |
0.878 | 1.033 | 0.685 | 1.558 | ||||
| Lymph node yes vs. no |
0.001 | 2.236 | 1.373 | 3.641 | 0.004 | 0.477 | 0.288 | 0.788 |
| Clinical stage III/IV vs. II/I |
0.807 | 0.894 | 0.363 | 2.202 | ||||
| TXLNA expression High vs. low |
0.018 | 1.811 | 1.109 | 2.958 | 0.048 | 1.641 | 1.003 | 2.685 |
| DFI | ||||||||
| Age >65 vs. ≤65 |
0.287 | 0.787 | 0.507 | 1.222 | ||||
| Female vs. male | 0.661 | 0.908 | 0.591 | 1.396 | ||||
| Smoking history 2/3/4/5 vs. 1 |
0.502 | 1.173 | 0.736 | 1.868 | ||||
| Alcohol history Yes vs. no |
0.382 | 0.810 | 0.504 | 1.300 | ||||
| Lymph node Yes vs. no |
0.033 | 0.585 | 0.358 | 0.957 | 0.048 | 0.601 | 0.363 | 0.996 |
| Clinical stage III/IV vs. II/I |
0.328 | 0.561 | 0.176 | 1.786 | ||||
| TXLNA expression High vs. low |
0.016 | 1.999 | 1.139 | 3.509 | 0.033 | 1.848 | 1.051 | 3.250 |
| PFI | ||||||||
| Age >65 vs. ≤65 |
0.159 | 1.318 | 0.897 | 1.937 | ||||
| Female vs. male | 0.815 | 0.956 | 0.656 | 1.394 | ||||
| Smoking history 2/3/4/5 vs. 1 |
0.786 | 1.059 | 0.7 | 1.602 | ||||
| Alcohol history Yes vs. no |
0.63 | 0.902 | 0.593 | 1.372 | ||||
| Lymph node Yes vs. no |
0.004 | 0.524 | 0.336 | 0.819 | 0.012 | 0.558 | 0.354 | 0.881 |
| Clinical stage III/IV vs. II/I |
0.922 | 1.039 | 0.481 | 2.247 | ||||
| TXLNA expression High vs. Low |
0.017 | 1.8 | 1.113 | 2.912 | 0.038 | 1.668 | 1.029 | 2.702 |
| DSS | ||||||||
| Age >65 vs. ≤65 |
0.640 | 1.115 | 0.706 | 1.762 | ||||
| Female vs. male | 0.500 | 0.855 | 0.543 | 1.347 | ||||
| Smoking history 2/3/4/5 vs. 1 |
0.463 | 0.827 | 0.498 | 1.373 | ||||
| Alcohol history Yes vs. no |
0.493 | 0.835 | 0.498 | 1.398 | ||||
| Lymph node Yes vs. no |
0.004 | 0.411 | 0.226 | 0.750 | 0.01 | 0.438 | 0.234 | 0.82 |
| Clinical stage III/IV vs. II/I |
0.561 | 1.311 | 0.526 | 3.270 | ||||
| TXLNA expression High vs. low |
0.050 | 1.802 | 1.000 | 3.247 | 0.103 | 1.635 | 0.906 | 2.951 |