Table 3. The expression of the arachidonic acid metabolism pathway-related genes in microarray training datasets and the OE RNA-sequencing validation dataset GSE105764.
| Gene Symbol | Gene Description | OE RNA-sequencing dataset GSE105764 | The merged OE dataset of GSE7305 and GSE7307 | The individual PE dataset E-MTAB-694 | The individual DIE dataset GSE25628 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Log2FC | P-Value | Log2FC | P-Value | Log2FC | P-Value | Log2FC | P-Value | ||
| PTGIS | Prostaglandin I2 Synthase | 6.289598638 | 2.43946E-44 | 4.631282825 | 2.91622E-16 | 4.971203942 | 1.20213E-16 | 3.508766958 | 0.002253242 |
| PLA2G2A | Phospholipase A2 Group IIA | 2.822326237 | 0.001074114 | 4.849610555 | 2.38055E-25 | 3.551202751 | 3.01372E-06 | 3.152761244 | 0.010549907 |
| GGT5 | Gamma-Glutamyltransferase 5 | 2.682418539 | 1.54252E-12 | 1.03319199 | 1.421E-13 | 1.031785388 | 5.90453E-07 | 1.32309443 | 0.006376396 |
| CYP2J2 | Cytochrome P450 Family 2 Subfamily J Member 2 | −6.239846138 | 1.75094E-27 | −1.142837781 | 1.79003E-09 | −1.850912918 | 9.66805E-09 | −1.160485084 | 0.02902089 |
Notes.
- Log2 FC
- Log2 fold change
- OE
- ovarian endometriosis
- PE
- peritoneal endometriosis
- DIE
- deep infiltrating endometriosis