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The expression levels of Kelch-like ECH-assiciated protein-1 (KEAP1) and nuclear factor erythroid 2-related factor 2 (NRF2) in colonic epithelial cell lines, treated with tumor necrosis factor α (TNF-α) and/or 17β-estradiol (E2). (A) Protein expression level of KEAP1 and NRF2, during 0 to 6 hours of treatment. The mRNA expression levels of KEAP1 (B) and NRF2 (C) at 6 hours after treatment of TNF-α and/or E2. NS, not significant. ap < 0.05.
