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. Author manuscript; available in PMC: 2021 Mar 1.

Published in final edited form as: Clin Lung Cancer. 2019 Dec 20;21(2):127–135.e3. doi: 10.1016/j.cllc.2019.12.001

Table 2.

Univariable and multivariable analyses of disease recurrence. Recurrence (Yes/No) by all patients.

	# Recurrence		UVA			MVA with all variables			MVA after model selection
	No	Yes	OR (95% CI)	p	Overall p	OR (95% CI)	p	Overall p	OR (95% CI)	p	Overall p
Gender
Male	527	247	Reference		0.42	Reference		0.71	not used in MVA
Female	559	240	0.92 (0.74 - 1.13)	0.420	0.42	0.96 (0.75 - 1.21)	0.71	0.71

Age
<= 65	495	268	1.51 (1.22 - 1.88)	<0.001	<0.001	1.21 (0.95 - 1.55)	0.13	0.13	removed in model selection
>= 65	589	211	Reference		<0.001	Reference		0.13

Race
Caucasian	810	370	Reference		0.02	Reference		0.03	Reference		0.02
African American	182	60	0.72 (0.53 - 0.99)	0.044		0.67 (0.47 - 0.95)	0.02		0.68 (0.49 - 0.94)	0.020
Other	94	57	1.33 (0.93 - 1.89)	0.114		1.28 (0.87 - 1.88)	0.22		1.24 (0.86 - 1.79)	0.240

TNM Staging
1	651	186	Reference		<0.001	Reference		0.60	removed in model selection
2	168	81	1.69 (1.24 - 2.30)	0.001		1.10 (0.77 - 1.56)	0.61
3	214	140	2.29 (1.75 - 2.99)	<0.001		1.20 (0.85 - 1.69)	0.31

Histology
Small cell	39	44	2.67 (1.71 - 4.16)	<0.001	<0.001	1.428 (0.819 - 2.490)	0.21	0.21	removed in model selection
Other	1047	443	Reference		<0.001	Reference		0.21

Primary Treatment
Local therapy alone	742	211	0.35 (0.28 - 0.44)	<0.001	<0.001	0.42 (0.31 - 0.58)	<0.001	<0.001	0.35 (0.28 - 0.44)	<0.001	<0.001
Systemic therapy included	344	276	Reference		<0.001	Reference		<0.001	Reference		<0.001