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. Author manuscript; available in PMC: 2020 May 25.
Published in final edited form as: Mol Psychiatry. 2019 Sep 9;25(6):1334–1343. doi: 10.1038/s41380-019-0516-z

Figure 1. MWAS of baseline methylation and MDD status six years later.

Figure 1.

(A) Quantile-Quantile plot. The main diagonal of the plot indicates the P-values we would obtain assuming none of the CpGs predict MDD status six years later (MDDYear6) with the yellow curved lines denoting the 95% confidence intervals. The red points in the QQ plot are the observed MWAS P-values. (B) Manhattan plot. The plot shows the MWAS P-values by their chromosomal location. The dashed line indicates the threshold used for inclusion of CpGs in the MRS.