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. Author manuscript; available in PMC: 2020 May 25.
Published in final edited form as: Mol Psychiatry. 2019 Sep 9;25(6):1334–1343. doi: 10.1038/s41380-019-0516-z

Table 2.

Results GWAS enrichment analyses and co-localization analyses

External data Top MWAS MRS Overall
OR P-val. OR P-val. P-val.
PGC MDD GWAS meta 2.50 <10−5 2.36 <10−5 <10−5 *
GWAS cat. Inflammation* 1.03 0.44 1.26 <10−5 <10−5 *
GWAS cat. Infection* 1.20 0.13 1.09 0.08 0.08
GWAS cat. Autoimmune* 1.05 0.35 1.29 <10−5 <10−5 *
GTEx eQTLs BA24 1.46 <10−5 1.66 <10−5 <10−5 *
GTEx eQTLs BA9 1.52 <10−5 1.66 <10−5 <10−5 *
GTEx eQTLs whole blood 1.47 <10−5 1.62 <10−5 <10−5 *
McClay et. al. meQTLs 0.91 0.95 1.01 0.83 0.83

OR is odds ratio,

*

significant after correction for multiple testing. Number of SNPs in GWAS cat. inflammation, GWAS cat. infection, GWAS cat. Autoimmune was 919, 520, and 1843 respectively.