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. 2020 Feb 24;2020:5282949. doi: 10.1155/2020/5282949

Table 2.

Effect of phytoextracts on cancer cell line, HeLa.

Drug/phytoextracts Concentration Percentage cell viability
Control/untreated cell lines 100 ± 0.005
Curcumin 15 μM 49.85±0.05∗∗∗∗

Methanol extract Distilled water extract Chloroform extract
Whole fruit 50 μg/mL 89.80±0.007∗∗∗∗ 91.40±0.006∗∗∗∗ 86.12±0.004∗∗∗∗
Seeds 86.02±0.004∗∗∗∗ 84.36±0.004∗∗∗∗ 93.68±0.006∗∗∗∗
Whole fruit 150 μg/mL 75.25±0.005∗∗∗∗ 76.19±0.001∗∗∗∗ 72.46±0.005∗∗∗∗
Seeds 77.95±0.002∗∗∗∗ 77.95±0.002∗∗∗∗ 76.08±0.004∗∗∗∗
Whole fruit 250 μg/mL 46.27±0.003∗∗∗∗ 64.18±0.001∗∗∗∗ 51.35±0.005∗∗∗∗
Seeds 63.04±0.003∗∗∗∗ 61.07±0.005∗∗∗∗ 56.02±0.02∗∗∗∗
Whole fruit 350 μg/mL 32.60±0.007∗∗∗∗ 54.86±0.004∗∗∗∗ 32.40±0.005∗∗∗∗
Seeds 54.76±0.002∗∗∗∗ 50.51±0.005∗∗∗∗ 43.78±0.003∗∗∗∗
Whole fruit 450 μg/mL 18.32±0.004∗∗∗∗ 25.87±0.004∗∗∗∗ 14.59±0.005∗∗∗∗
Seeds 32.09±0.003∗∗∗∗ 36.12±0.002∗∗∗∗ 38.01±0.004∗∗∗∗

Comparative cytotoxic effect of different solvent extracts of honeydew melon on HeLa cell lines after 24 h of incubation. Data is expressed as the mean ± SD (each treatment, n = 3). ∗∗∗∗ indicates p < 0.0001 in comparison with control/untreated cells by one-way ANOVA followed by Dunnett's test for multiple comparisons.