. 2020 Feb 24;2020:5282949. doi: 10.1155/2020/5282949

Table 3.

Effect of phytoextracts on cancer cell line, HCT116.

Drug/phytoextracts	Concentration	Percentage cell viability
Control/untreated cell lines	—	100 ± 0.006
Curcumin	15 μM	50.63±0.003^∗∗∗∗

		Methanol extract	Distilled water extract	Chloroform extract
Whole fruit	50 μg/mL	80.15±0.007^∗∗∗∗	84.27±0.001^∗∗∗∗	89.25±0.01^∗∗∗∗
Seeds	50 μg/mL	80.35±0.004^∗∗∗∗	83.94±0.006^∗∗∗∗	80.40±0.007^∗∗∗∗
Whole fruit	150 μg/mL	70.53±0.003^∗∗∗∗	66.75±0.004^∗∗∗∗	73.98±0.003^∗∗∗∗
Seeds	150 μg/mL	68.81±0.007^∗∗∗∗	69.87±0.006^∗∗∗∗	70.40±0.01^∗∗∗∗
Whole fruit	250 μg/mL	49.30±0.007^∗∗∗∗	56.93±0.004^∗∗∗∗	60.45±0.007^∗∗∗∗
Seeds	250 μg/mL	48.50±0.007^∗∗∗∗	58.46±0.002^∗∗∗∗	47.37±0.002^∗∗∗∗
Whole fruit	350 μg/mL	31.25±0.007^∗∗∗∗	46.25±0.01^∗∗∗∗	42.01±0.007^∗∗∗∗
Seeds	350 μg/mL	37.35±0.003^∗∗∗∗	47.40±0.01^∗∗∗∗	30.12±0.01^∗∗∗∗
Whole fruit	450 μg/mL	28.46±0.003^∗∗∗∗	16.72±0.002^∗∗∗∗	27.07±0.004^∗∗∗∗
Seeds	450 μg/mL	22.49±0.01^∗∗∗∗	27.14±0.007^∗∗∗∗	18.97±0.004^∗∗∗∗

Comparative cytotoxic effect of different solvent extracts of honeydew melon on HCT116 cell lines after 24 h of incubation. Data is expressed as the mean ± SD (each treatment, n = 3). ∗∗∗∗ indicates p < 0.0001 in comparison with control/untreated cells by one-way ANOVA followed by Dunnett's test for multiple comparisons.