Table 5.
Effect of honeydew melon phytoextracts on cancer cell line, Jurkat.
| Drug/phytoextracts | Concentration | Percentage cell viability | ||
| Control/untreated cell lines | — | 100 ± 0.009 | ||
| Curcumin | 15 μM | 43.10±0.007∗∗∗∗ | ||
|
| ||||
| Methanol extract | Distilled water extract | Chloroform extract | ||
| Whole fruit | 50 μg/mL | 79.48±0.006∗∗∗∗ | 90.77±0.007∗∗∗∗ | 87.81±0.001∗∗∗∗ |
| Seeds | 87.45±0.009∗∗∗∗ | 73.63±0.002∗∗∗∗ | 88.62±0.004∗∗∗∗ | |
| Whole fruit | 150 μg/mL | 68.27±0.002∗∗∗∗ | 85.03±0.004∗∗∗∗ | 67.74±0.004∗∗∗∗ |
| Seeds | 71.59±0.002∗∗∗∗ | 66.21±0.002∗∗∗∗ | 74.55±0.001∗∗∗∗ | |
| Whole fruit | 250 μg/mL | 46.32±0.004∗∗∗∗ | 69.62±0.006∗∗∗∗ | 52.68±0.004∗∗∗∗ |
| Seeds | 58.06±0.004∗∗∗∗ | 56.36±0.003∗∗∗∗ | 47.31±0.004∗∗∗∗ | |
| Whole fruit | 350 μg/mL | 34.1±0.003∗∗∗∗ | 52.86±0.005∗∗∗∗ | 29.65±0.003∗∗∗∗ |
| Seeds | 43.99±0.003∗∗∗∗ | 47.04±0.002∗∗∗∗ | 32.61±0.009∗∗∗∗ | |
| Whole fruit | 450 μg/mL | 16.68±0.002∗∗∗∗ | 38.08±0.006∗∗∗∗ | 11.55±0.003∗∗∗∗ |
| Seeds | 27.41±0.008∗∗∗∗ | 28.13±0.005∗∗∗∗ | 16.12±0.008∗∗∗∗ | |
Comparative cytotoxic effect of different solvent extracts of honeydew melon on Jurkat cell lines after 24 h of incubation. Data is expressed as the mean ± SD (each treatment, n = 3). ∗∗∗∗ indicates p < 0.0001 in comparison with control/untreated cells by one-way ANOVA followed by Dunnett's test for multiple comparisons.