Table 2.

Genotype distribution and allele frequencies of the human oxidative stress-related gene in cases and controls.

		Genotype frequency of cases			Genotype frequency of controls			Genotype frequency		Minor allele	Minor allele frequencies
SNP ID (allele1/allele2)	Position	1/1	1/2	2/2	1/1	1/2	2/2	χ 2	p		Case	Control	χ 2	p	OR	95% CI
rs1695 (A/G)	67585218	394	214	23	452	235	33	0.885	0.642	G	0.206	0.209	0.037	0.848	1.018	0.845-1.227
rs4680 (A/G)	19963748	48	227	356	52	273	395	0.120	0.758	A	0.256	0.262	0.120	0.729	0.970	0.816-1.153
rs1800566 (C/T)	69711242	177	330	124	219	337	164	4.239	0.120	C	0.458	0.462	0.039	0.843	1.015	0.873-1.182
rs4807542 (A/G)	1104079	9	118	504	7	149	564	1.363	0.506	A	0.108	0.113	0.201	0.654	0.946	0.743-1.204
rs713041 (C/T)	1106616	216	296	119	204	359	157	5.796	0.055	T	0.423	0.467	5.322	0.021	1.196	1.027-1.393
rs7579 (A/G)	42800706	51	249	331	48	302	370	1.502	0.472	A	0.278	0.276	0.010	0.920	1.009	0.852-1.194
rs230813 (C/G)	42798931	105	276	250	104	353	263	3.914	0.141	C	0.385	0.390	0.057	0.811	0.981	0.840-1.146
rs1004467 (C/T)	102834750	80	279	272	97	326	297	0.522	0.770	C	0.348	0.361	0.516	0.473	0.944	0.806-1.105
rs3824755 (C/G)	102836092	72	278	281	85	334	301	1.029	0.598	C	0.334	0.35	0.728	0.394	0.933	0.796-1.094
rs9932581 (C/T)	88651945	107	337	187	159	355	206	5.714	0.057	C	0.437	0.467	2.567	0.109	0.883	0.759-1.028

Table 2 shows the results of oxidative stress-related genotype distribution and allele frequencies in PE and control groups. After correction for multiple comparisons (P/10), there was no significant difference at the oxidative stress-related SNPs among 10 groups, although the SNP rs713041 with a C/T polymorphism, the T allele looks like a risk allele for predisposition to PE (minor allele χ² = 5.322, p = 0.021, p < 0.05; OR = 1.196, 95%CI = 1.027‐1.393). Similarly, for all other SNPs in Table 2, there were no significant differences in the remaining SNP loci between PE and control groups (rs1695: for genotype, p = 0.642, for allele, χ² = 0.037, p = 0.848, OR = 1.018, 95%CI = 0.845‐1.227; rs4680: for genotype, p = 0.758, for allele, χ² = 0.120, p = 0.729, OR = 0.970, 95%CI = 0.816‐1.153; rs1800566: for genotype, p = 0.120, for allele, χ² = 0.039, p = 0.843, OR = 1.015, 95%CI = 0.873‐1.182; rs4807542: for genotype, p = 0.506, for allele, χ² = 0.201, p = 0.654, OR = 0.946, 95%CI = 0.743‐1.204; rs713041: for genotype, p = 0.055; rs7579: for genotype, p = 0.472, for allele, χ² = 0.010, p = 0.920, OR = 1.009, 95%CI = 0.852‐1.194; rs230813: for genotype, p = 0.141, for allele, χ² = 0.057, p = 0.811, OR = 0.981, 95%CI = 0.840‐1.146; rs1004467: for genotype, p = 0.770, for allele, χ² = 0.516, p = 0.473, OR = 0.944, 95%CI = 0.806‐1.105; rs3824755: for genotype, p = 0.598, for allele, χ² = 0.728, p = 0.394, OR = 0.933, 95%CI = 0.796‐1.094; rs9932581: for genotype, p = 0.057, for allele, χ² = 2.567, p = 0.109, OR = 0.883, 95%CI = 0.759‐1.028).