Table 3. Differences of serum inflammatory mediators measured at the recovery phase according to the severity of anaphylaxis and the cut-off values of psychiatric questionnaires (IES-R-K, K-BAI, and K-BDI).
| Mediators | Severity of anaphylaxis | IES-R-K | K-BAI | K-BDI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nonsevere (n = 67) | Severe (n = 75) | P value | ≥ 25 (n = 58) | < 25 (n = 84) | P value | ≥ 22 (n = 36) | < 22 (n = 106) | P value | ≥ 17 (n = 40) | < 17 (n = 102) | P value | |
| Tryptase (ng/mL) | 3.6 ± 2.1 | 3.5 ± 2.7 | 0.741 | 3.2 ± 2.5 | 3.8 ± 2.4 | 0.050 | 3.3 ± 2.7 | 3.6 ± 2.3 | 0.261 | 3.2 ± 2.8 | 3.7 ± 2.3 | 0.072 |
| IL-6 (pg/mL) | 5.3 ± 11.0 | 9.3 ± 25.2 | 0.223 | 8.2 ± 20.8 | 6.9 ± 19.2 | 0.434 | 4.6 ± 10.6 | 8.4 ± 22.0 | 0.460 | 5.1 ± 13.0 | 8.3 ± 21.9 | 0.105 |
| TNF-α (pg/mL) | 0.8 ± 4.1 | 1.4 ± 7.7 | 0.594 | 1.1 ± 4.8 | 1.1 ± 7.1 | 0.797 | 1.8 ± 6.0 | 0.9 ± 6.4 | 0.511 | 1.5 ± 5.7 | 1.0 ± 6.5 | 0.757 |
| CRP (µg/mL) | 1.1 ± 0.8 | 1.2 ± 0.9 | 0.636 | 1.0 ± 0.8 | 1.2 ± 0.9 | 0.338 | 1.0 ± 0.9 | 1.2 ± 0.8 | 0.265 | 0.9 ± 0.8 | 1.2 ± 0.9 | 0.069 |
| PAF (ng/mL) | 4.5 ± 3.2 | 4.4 ± 3.2 | 0.868 | 4.0 ± 3.0 | 4.8 ± 3.3 | 0.156 | 3.6 ± 3.0 | 4.8 ± 3.2 | 0.045 | 3.5 ± 2.8 | 4.9 ± 3.3 | 0.028 |
IES-R-K, the Impact of Event Scale-Revised-Korean version; K-BAI, Korean version of the Beck Anxiety Inventory; K-BDI, Korean version of the Beck Depression Inventory; IL-6, interlukin-6; TNF-α, tumor necrosis factor-α; CRP, C-reactive protein; PAF, platelet-activating factor.