Table 4. Incidence of DILI by causative agent.

Causative agents	DILI (Number)	Total No. of prescribed patients† during the study period (Number)	Crude incidence of DILI (%) per 1,000 prescribed patients*	95% CI
Piperacillin-tazobactam	38	12,001	3.2	2.2–4.2
Methotrexate	31	1,596	19.4	12.7–26.2
Acetaminophen	29	73,262	0.4	0.3–0.5
Ceftriaxone	25	21,838	1.2	0.7–1.6
TPN	24	26,591	0.9	0.5–1.3
Vancomycin	16	6,899	2.3	1.2–3.5
Meropenem	14	5,307	2.6	1.3–4.0
Cytosine arabinoside	11	597	18.4	7.6–29.2

DILI, drug-induced liver injury; CI, confidence interval; TPN, total parental nutrition.

^*,†Prescribed patients were those who were prescribed the drug of interest more than once regardless of the occurrence of DILI.