Table 3. Multiple logistic regression analysis of predictors of exacerbation in EA and NEA.
| Characteristics | EA (≥ 65 yr) | NEA (< 65 yr) | ||
|---|---|---|---|---|
| aOR (95% CI) | P value | aOR (95% CI) | P value | |
| Fixed airway obstruction | 13.23 (5.96–31.61) | < 0.001 | 3.46 (0.61–7.51) | 0.154 |
| Chronic rhinosinusitis | 3.21 (1.11–4.54) | 0.027 | 0.76 (0.46–1.25) | 0.291 |
| Blood eosinophil (count) | 1.01 (0.99–1.02) | 0.971 | 1.02 (1.01–1.21) | 0.019 |
| Sex (male) | 1.89 (1.13–3.19) | 0.015 | 1.03 (0.99–1.08) | 0.062 |
| Age (yr) | 0.97 (0.91–1.05) | 0.560 | 1.34 (0.77–1.79) | 0.099 |
| BMI (kg/m2) | 0.99 (0.91–1.09) | 0.930 | 1.01 (0.94–1.09) | 0.755 |
| Smoking status | 0.55 (0.21–1.35) | 0.200 | 0.99 (0.46–2.09) | 0.977 |
| Symptom duration (yr) | 0.14 (0.98–1.10) | 0.120 | 0.98 (0.92–1.04) | 0.497 |
| Baseline FVC_absolute | 1.07 (0.41–2.80) | 0.870 | 1.17 (0.14–1.89) | 0.879 |
| Baseline FEV1_absolute | 0.43 (0.09–1.82) | 0.260 | 1.59 (0.59–2.73) | 0.744 |
| Baseline_FEV1/FVC ratio | 1.01 (0.99–1.02) | 0.090 | 0.93 (0.86–1.01) | 0.090 |
| Atopy | 1.07 (0.47–2.36) | 0.870 | 1.37 (0.78–2.42) | 0.273 |
EA, elderly asthma; NEA, non-elderly asthma; aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.