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. 2020 Jan 5;5:10. doi: 10.21037/tgh.2019.09.09

Table 3. Previous studies that have assessed the impact of obesity on survival in post-liver transplant patients.

Study name Period BMI (kg/m2) Patient survival (%)    Other complications
N 30-day 90-day 1 year 3-year 5-year
Nair et al. (20) 1988–1996 Obese BMI <25 2,611 92 86 53 ● 1-, 3-, 5-year mortality was high in severely obese (BMI >40) group compared to non-obese group
Non obese BMI >30 8,382 94 84 56 ● Intraoperative mortality was similar between groups
Boin et al. (61) 1991–2006 Obese BMI >30; mean BMI 34 38 61.3 51 ● Postop creatinine was higher in obese group. Operative times, blood transfusion and ICU stay similar in both groups. Survival was similar in both groups
Non obese BMI 18.5–29.9; mean BMI 24 206 68 47
Braunfeld et al. (62) 1992–1996 Obese mean BMI 36.2 40 78 68 ● Intraoperative and post-operative complications are same
Non obese; mean BMI 23.4 61 86 75 ● Length of surgery and transfusion requirement was same
● Length of ICU stay and wound complications are similar
Conzen et al. (63) 2002–2012 Obese BMI >30 513 51.3 ● Operative times, ICU stay, perioperative complications and survival at 1 and 3 years similar between both groups
Non obese BMI 18–29.9 272 78.8
Fujikawa et al. (64) 1990–2005 Obese BMI >30 167 86 71 ● No differences in graft survival or patient’s survival, hospital stay, operative complications
Non obese BMI <25 288 82 67
Hakeem et al. (65) 1994–2009 Obese BMI >30 145 86 78 70 ● No difference in patient and graft survival noticed
Non obese BMI 18–25 643 80 76 70 ● Morbidly obese patients had increased ICU stay
● No change in blood transfusions needed, post op complications
Hilling et al. (66) 1990–2003 Obese BMI >30 20 80 60 50 ● Operative time, transfusions needed, ICU stay was similar between both groups
Non obese BMI 19.1c29.3 20 90 85 80 ● Mortality higher in obese group
Lamattina et al. (67) 1997–2008 Obese BMI >30 (35-40) 83 91 78 78 ● Operative time, ICU stay, transfusions needed were higher in obese group
Non obese BMI 18–25 216 94 86 83
Leonard et al. (68) 1990–1994 and 1998–2006 Obese BMI >35 69 97 80 88 ● No difference in patient and graft survival
Non obese BMI 18.5–25 561 98 89 80 ● ICU stay was similar in all groups except in class 3 obesity
Mathur et al. (69) 1996–2008 Obese BMI >30 58 4 ● Primary graft dysfunction was similar in both groups
Non obese BMI <25 47 3
N 30-day 90-day 1 year 3-year 5-year
Nair et al. (70) 1994–1996 Obese BMI (>31.1 for men and 32.3 for women) 21 90 66 ● Length of hospital stay was higher in both obese and severely obese patients
● Number of blood transfusions was similar in all groups
Non obese BMI (BMI <27.3 for men and <27.8 for women) 64 89 79 ● Survival rate similar in all groups
● Post-transplant complications highest in obesity group
Perez-Protto et al. (71) 2005–2011 Obese BMI >38 47 94 85 ● ICU stay and blood transfusion needed were common between both groups
Non obese BMI 20–26 183 78 76 ● Patient and graft survival similar in both groups
Sawyer et al. (72) 1989–1996 Obese BMI >35 26 77 ● Patient and graft survival similar between both groups
Non obese BMI <30 202 81 ● Wound infections were higher in obese groups after transplant but other long-term outcomes are similar
Schalansky et al. (73) 2005–2014 Obese BMI >35 8,356 92.5 84.1 78.5 ● Patients with obesity are at increased risk of mortality compared to normal weight patients
Non obese BMI <30 969 92.2 84.4 78.8
Singal et al. (74) 1988–2011 Obese BMI>35 22 96 ● Patient and graft survival at 1 year similar between 2 groups
Non obese BMI 18.5–24.9 79 89
Werneck et al. (75) 2007–2009 Obese BMI >30 32 75 ● Patient survival and ICU stay similar between both groups
Non obese BMI 18.5–24.99 46 91
Bhambha et al. (76) 2002–2011 Obese BMI>35 4062 94 88 ● Patient and graft survival were similar in both groups
Non obese BMI 18.5-24.9 13,262 95 88
Beal et al. (77) 2003–2013 Obese BMI >30 17,339 96 92 90 ● Patient mortality more in obese group
Non obese BMI <30 34,217 97 91 89