Table 1.
Bolondi criteria
| BCLC sub-stage | B1 | B2 | B3 | B4 |
| CPT score | 5-7 | 5-6 | 7 | 8-91 |
| Beyond Milan and within Ut-7 | In | Out | Out | Any |
| ECOG (tumor related) PS | 0 | 0 | 0 | 0-1 |
| PVT | No | No | No | No |
| 1st option | TACE | TACE or TARE | BSC | |
| Alternative | LT TACE + ablation | SOR | Research trials TACE SOR | LT2 |
1
With severe/refractory ascites and/or jaundice.
2
Only if Up-to-7 IN and PS0. CPT: Child Pugh score; BSC: Best supportive care; LT: Liver transplantation; SOR: Sorafenib; TACE: Transcatheter arterial chemoembolization; TARE: Transarterial radioembolization; PVT: Portal vein thrombosis; Ut-7: Up to-7 criteria.