Mexico 1992.
Methods | Please see details below. | |
Participants | 38 women > 28 weeks' gestation with SBP >/= 150 mmHg, DBP >/= 110 mmHg, proteinuria 2+, no previous treatment, at least 1 symptom (of headache, blurred vision, epigastric pain) and no epilepsy. | |
Interventions | MgSO4: 4 g IV over 15 min, then 1 g/hr infusion. Diazepam: 30 mg in 500 ml 5% glucose IV at 60 microg/hr. If convulsions, bolus of 10 mg IV. |
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Outcomes | Woman: eclampsia, caesarean section. Baby: mean Apgar scores (1 and 5 min). |
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Notes | Nifedipine for BP control. Translated from the Spanish. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | "Permuted block randomisation" using random number tables. |
Allocation concealment? | Unclear risk | Allocation was by sealed, numbered envelopes. |
Blinding? All outcomes | Unclear risk | Not described. |
Incomplete outcome data addressed? All outcomes | Unclear risk | The total number of women eligible for trial entry is not described. |