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. 2010 Jul 7;2010(7):CD001563. doi: 10.1002/14651858.CD001563.pub3

Brehler 2006.

Methods Randomised, placebo‐controlled, double‐blind, parallel‐group design
Participants 32 patients of mean age 37.2 years with proven sensitivity to house dust mite and symptoms of rhinoconjunctivitis
Interventions House dust mite impermeable bedding
Outcomes Symptom scores
Use of anti‐allergic medication
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk "... the volunteers were randomised to receive either active or placebo encasings"
Allocation concealment? Unclear risk "... the covers for mattresses, pillows, and duvets or blankets were handed out in numbered packages"
Blinding? Unclear risk Insufficient information
Incomplete outcome data addressed? 
 All outcomes High risk 11 of the 32 patients enrolled did not complete the study; an intention‐to‐treat analysis was not undertaken
Free of selective reporting? Low risk
Free of other bias? High risk The authors compared the outcome measures within the 2 arms not between them as required