Brehler 2006.
Methods | Randomised, placebo‐controlled, double‐blind, parallel‐group design | |
Participants | 32 patients of mean age 37.2 years with proven sensitivity to house dust mite and symptoms of rhinoconjunctivitis | |
Interventions | House dust mite impermeable bedding | |
Outcomes | Symptom scores Use of anti‐allergic medication |
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Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | "... the volunteers were randomised to receive either active or placebo encasings" |
Allocation concealment? | Unclear risk | "... the covers for mattresses, pillows, and duvets or blankets were handed out in numbered packages" |
Blinding? | Unclear risk | Insufficient information |
Incomplete outcome data addressed? All outcomes | High risk | 11 of the 32 patients enrolled did not complete the study; an intention‐to‐treat analysis was not undertaken |
Free of selective reporting? | Low risk | — |
Free of other bias? | High risk | The authors compared the outcome measures within the 2 arms not between them as required |