Brehler 2006.
| Methods | Randomised, placebo‐controlled, double‐blind, parallel‐group design | |
| Participants | 32 patients of mean age 37.2 years with proven sensitivity to house dust mite and symptoms of rhinoconjunctivitis | |
| Interventions | House dust mite impermeable bedding | |
| Outcomes | Symptom scores Use of anti‐allergic medication |
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| Notes | — | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Adequate sequence generation? | Unclear risk | "... the volunteers were randomised to receive either active or placebo encasings" |
| Allocation concealment? | Unclear risk | "... the covers for mattresses, pillows, and duvets or blankets were handed out in numbered packages" |
| Blinding? | Unclear risk | Insufficient information |
| Incomplete outcome data addressed? All outcomes | High risk | 11 of the 32 patients enrolled did not complete the study; an intention‐to‐treat analysis was not undertaken |
| Free of selective reporting? | Low risk | — |
| Free of other bias? | High risk | The authors compared the outcome measures within the 2 arms not between them as required |